Digital Biomarkers

Connected medication package and wearable activity recognition algorithms.

Background

Poor medication adherence is often responsible for poor outcomes. Doctors, patients, and Pharma need a system to passively and accurately monitor medication adherence.

Approach

Circadic created a connected, multidose pouch system that can detect when a particular pouch has been opened to release its payload. A wearable-based activity recognition algorithm can then track activities that follow the opening of the pouch and are related to the action of consuming oral medication.  

Under the hood

Circadic has developed a proprietary system that detects when a medication pouch has been torn open and thus the medication payload can be delivered. The system consists of a printed circuit that runs the entire roll of pouches and is equipped with a transmission unit that communicates events to the cloud. Following an event, the wearable-based activity recognition algorithm looks for motion and sound patterns, related to the swallowing of oral medication, to confirm delivery of the medication. The system was shown to perform with a 92% accuracy in a real-world setup.